Fig. 4
From: Imaging-based diagnosis of sarcopenia for transplant-free survival in primary sclerosing cholangitis
Comparison of five-year transplant-free survival after imaging in patients with PSC meeting German standard exception criteria (2022) versus modified criteria, indicated by Kaplan-Meier curves
Juxtaposition of two Kaplan-Meier analyses depicting transplant-free survival (TFS) of n = 95 patients with PSC at 5 years after last cross-sectional imaging. Two different sets of MELD SE criteria for PSC were used to compare predictive accuracy regarding TFS: a) SEG (Standard Exception criteria Germany used until 12th September 2023) on the left side versus b) M-SEG (Modified-SEG) on the right side, which includes detection of sarcopenia via L3-SMI as third criterion instead of BMI reduction >10% in 12 months
Log-rank test p < 0.001 for both analyses. Censored patients shown as + Results:
a) TFS at 5 years of patients with SEG status was 11.5% versus 68.1% in patients without SE status
b) TFS at 5 years of patients with M-SEG status was 22.7% versus 78.4% in patients without SE status