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  1. Cancer-associated fibroblasts (CAFs) have been reported to exhibit protumorigenic effects. Among the well-known CAF markers such as smooth muscle actin (SMA) and fibroblast activation protein (FAP), high expre...

    Authors: Yuhei Waki, Yuji Morine, Takayuki Noma, Chie Takasu, Hiroki Teraoku, Shinichiro Yamada, Yu Saito, Tetsuya Ikemoto and Mitsuo Shimada
    Citation: BMC Gastroenterology 2023 23:415
  2. There are different therapeutic approaches for biliary strictures and reducing portal hypertension in patients with symptomatic portal cavernoma cholangiopathy (PCC). Endoscopic treatment includes endoscopic b...

    Authors: Abdullah Murat Buyruk, Çağdaş Erdoğan, Fatih Tekin, İlker Turan, Ömer Özütemiz and Galip Ersöz¹
    Citation: BMC Gastroenterology 2023 23:414
  3. Common variable immunodeficiency disorder (CVID) patients may have gastrointestinal (GI) involvement and suffer from infections, which are poorly understood. This study aimed to evaluate the clinical, endoscop...

    Authors: Yang Chen, Yan You, Ji Li, Aiming Yang, Weixun Zhou and Xiaoqing Li
    Citation: BMC Gastroenterology 2023 23:413
  4. Novel endoscopic techniques used in the treatment of gastric lesions with local submucosal fibrosis need preclinical evaluation and training due to safety limitations. Therefore, the purpose of our study was t...

    Authors: Xiao-Jian He, Xiao-Ling Wang, Chuan-Shen Jiang, Dong-Gui Hong, Hai-Lan Lin, Yun-Ping Zheng, Han Li, Xin-Jiang Chen, Jian-Xiao Huang, Ling-Shuang Dai, Mei-Yan Liu, Bao-Xiang Luo, Dong-Liang Li, Da-Zhou Li and Wen Wang
    Citation: BMC Gastroenterology 2023 23:412
  5. T cell transfer colitis model is often used to study the CD4+ T cell functions in the intestine. However, the specific roles of macrophages in colitis remain unclear. In this study, we aimed to evaluate the pheno...

    Authors: Shin Ebihara, Toshiki Urashima, Wataru Amano, Hideto Yamamura and Noriko Konishi
    Citation: BMC Gastroenterology 2023 23:411
  6. Life-threatening bleeding following endoscopic variceal ligation (EVL) in patients with cirrhosis rarely can occur. The present study aimed to evaluate the performance of computed tomography (CT) in predicting...

    Authors: Hwaseong Ryu, Tae Un Kim, Ki Tae Yoon and Young Mi Hong
    Citation: BMC Gastroenterology 2023 23:410
  7. To present a study to identify the characteristics of coexisting early gastric cancer (EGC) and benign submucosal lesions, with the aim of reducing the adverse consequences of overdiagnosis and overtreatment.

    Authors: Huawei Yang, Zhen Li, Zhi Wei, Guodong Li, Yi Li, Shanbin Wu and Rui Ji
    Citation: BMC Gastroenterology 2023 23:409
  8. Gastrointestinal Neuroendocrine Neoplasms (GI-NENs) often result in liver metastases, and the role of Primary Tumor Resection (PTR) in managing GI-NENs with liver metastases (GI-NENLM) is still debated. This s...

    Authors: Yifan Liu, Zhixiong Wang, Qi Lin, Ruizhe Cui, Wei Tang, Guanghua Li and Zhao Wang
    Citation: BMC Gastroenterology 2023 23:408
  9. Women experience more severe gastrointestinal (GI) symptoms compared to men. The onset of puberty and the menstrual cycle may influence these differences. Additionally, health anxiety is an important construct...

    Authors: Sivanne Mendelson, Preethashree Anbukkarasu, Jeffrey E. Cassisi and Widaad Zaman
    Citation: BMC Gastroenterology 2023 23:406
  10. Many patients with ulcerative colitis (UC) gain weight after treatment. However, the clinical significance of weight gain in these patients remains unclear. This study aimed to evaluate body weight changes aft...

    Authors: Hyuk Yoon, Young Soo Park, Jeong Eun Shin, Byong Duk Ye, Chang Soo Eun, Soon Man Yoon, Jae Myung Cha, You Sun Kim, Kyu Chan Huh, Young Sook Park, Jae Hee Cheon, Eun Suk Jung, Youngdoe Kim and Su Young Jung
    Citation: BMC Gastroenterology 2023 23:405
  11. Very early-onset inflammatory bowel disease (VEOIBD) with interleukin-10 (IL10R) signaling deficiency usually requires enterostomy in patients who are refractory to traditional treatment. This study aimed to e...

    Authors: Zifei Tang, Song Sun, Min Ji, Peng Shi, Yuhuan Wang, Zhiheng Huang and Ying Huang
    Citation: BMC Gastroenterology 2023 23:404
  12. To date, an increasing number of studies have revealed that GP73 may have prognostic value in liver cancer. However, most of the studies evaluated serum GP73, and the results regarding the prognostic value of ...

    Authors: Wei-Ming Yu, Guo-Wei Li, Ming-Geng Lou and Zheng-Yu Wu
    Citation: BMC Gastroenterology 2023 23:401
  13. Primary biliary cholangitis (PBC) is a chronic cholestatic liver disease characterized by inflammation of the interlobular bile ducts. Ursodeoxycholic acid (UDCA) is the only FDA approved first-line therapy fo...

    Authors: Huiling Zhu, Mengyao Zheng, Haiyu He, Hongtao Lei, Wenlin Tai and Jinhui Yang
    Citation: BMC Gastroenterology 2023 23:400
  14. Infiltration of CD8 + T cells in the tumor microenvironment is correlated with better prognosis in various malignancies. Our study aimed to investigate vital genes correlated with CD8 + T cell infiltration in ...

    Authors: Dun Pan, Hui Chen, Jiaxiang Xu, Xin Lin and Liangqing Li
    Citation: BMC Gastroenterology 2023 23:399
  15. Appendiceal tumors represent a range of histologies that vary in behavior. Recommendations for treatment with appendectomy versus right hemicolectomy (RHC) for different tumor types are evolving and sometimes ...

    Authors: Victoria A. Marks, Daniel Kerekes, Samuel Butensky, Nita Ahuja, Caroline Johnson, Kiran Turaga and Sajid A. Khan
    Citation: BMC Gastroenterology 2023 23:398
  16. Acute nonvariceal upper gastrointestinal bleeding (ANVUGIB) is a common clinical emergency. Transcatheter arterial embolization (TAE) is usually used to locate the bleeding site and provide interventional embo...

    Authors: Yinong Zhu, Wenjuan Yang, Yuyan Zhang, Liansong Ye and Bing Hu
    Citation: BMC Gastroenterology 2023 23:396
  17. Chronic diarrhea is difficult to prevent and treat due to its complex etiology and pathogenesis. It places a huge burden on patients and public healthcare. It is known that the regulation of body homeostasis r...

    Authors: Xiaotong Li, Jiali Li, Zhiqun Cao and Nan Kang
    Citation: BMC Gastroenterology 2023 23:394
  18. Endoscopy is currently recognized as the gold standard for assessing inflammatory bowel disease (IBD) severity. However, because the procedure is costly and invasive, endoscopy is not suitable for frequently m...

    Authors: Jun Huang, Jie Lu, Feiyu Jiang and Tiejun Song
    Citation: BMC Gastroenterology 2023 23:393
  19. Endoscopic self-expandable metal stent (SEMS) placement is the key endoscopic treatment for unresectable malignant biliary obstruction. The benefit of covered SEMS over uncovered SEMS remains unknown as are ri...

    Authors: Nottawan Suksai, Patarapong Kamalaporn, Supphamat Chirnaksorn and Sukanya Siriyotha
    Citation: BMC Gastroenterology 2023 23:392
  20. The aim of this study was to determine whether serum vitamin D levels are associated with H. pylori infection and whether low serum vitamin D levels are an independent risk factor for H. pylori infection.

    Authors: Dan Liu, Li Ren, Dapeng Zhong, Wei Zhang, Wen Wen Li, Jie Liu and Chuan Han
    Citation: BMC Gastroenterology 2023 23:391
  21. Hepatitis B virus (HBV)-associated hepatocellular carcinoma (HCC) is one of the most common and deadly cancer and often accompanied by varying degrees of liver damage, leading to the dysfunction of fatty acid ...

    Authors: Ping Yan, Yunhai Luo, Zuotian Huang, Tong Mou, Hang Yang, Dadi Peng and Zhongjun Wu
    Citation: BMC Gastroenterology 2023 23:390
  22. Texture and color enhancement imaging (TXI) enhances the changes in endoscopic features caused by gastric neoplasms, such as redness/whiteness and elevation/depression. This study aimed to demonstrate the effe...

    Authors: Toshiki Futakuchi, Akira Dobashi, Hideka Horiuchi, Hiroto Furuhashi, Hiroaki Matsui, Yuko Hara, Masakuni Kobayashi, Shingo Ono, Naoto Tamai, Kazutaka Gomisawa, Takashi Yamauchi, Machi Suka and Kazuki Sumiyama
    Citation: BMC Gastroenterology 2023 23:389
  23. Oral nucleoside (acid) analogues (NAs) are recommended for patients with acute-on-chronic liver failure (ACLF) associated with hepatitis B virus (HBV-ACLF). The efficacy and safety of tenofovir (TDF) and entec...

    Authors: Neng Wang, Sike He, Yu Zheng and Lichun Wang
    Citation: BMC Gastroenterology 2023 23:388
  24. The majority of HBeAg-positive mothers with chronic hepatitis B have high levels of viremia and inactive disease with normal alanine aminotransferase (ALT) during pregnancy. In addition, postpartum disease act...

    Authors: Shi OuYang, Ziren Chen, Tingting Peng, Yawen Geng, Junchao Qiu, Zhirong Xiao and Calvin Q. Pan
    Citation: BMC Gastroenterology 2023 23:387
  25. Hepatitis C virus (HCV) infection is one of the main causes of liver cancer and imposes an enormous social and economic burden. The blood-borne virus screening policy for preventing iatrogenic infections rende...

    Authors: Lingling Zheng, Xiaoli Zhang, Yuxia Nian, Wenjuan Zhou, Dan Li and Yong Wu
    Citation: BMC Gastroenterology 2023 23:386
  26. Several studies have shown significant involvement of tumor-associated macrophages (TAMs) in the tumor microenvironment and cancer progression. However, no data on reliable TAM-related biomarkers are available...

    Authors: Hua Li, Lujuan Pan, Junyu Guo, JianLe Lao, Mingwei Wei and Fuda Huang
    Citation: BMC Gastroenterology 2023 23:385
  27. Nucleoside analogues are currently applied as a first-line treatment for chronic hepatitis B (CHB) patients. However, the long-term effects of this type of treatment on kidney and bone tissue need to be furthe...

    Authors: Zekun Liu, Zhenzhen Zhao, Xuefeng Ma, Shousheng Liu and Yongning Xin
    Citation: BMC Gastroenterology 2023 23:384
  28. The criteria for surgical intervention after non-curative endoscopic submucosal dissection (ESD) of early gastric cancer are unclear. We aimed to clarify the risk factors for residual cancer and lymph node met...

    Authors: Feng Sun, Yibo Huang, Yan Sun, Xingzhou Wang, Shichao Ai, Wenxian Guan and Meng Wang
    Citation: BMC Gastroenterology 2023 23:383
  29. Colon adenocarcinoma (COAD) is one of the most frequent types of cancer worldwide. Disulfidptosis has been identified as a new mode of cell death recently. The goal of this study was to explore the possibility...

    Authors: Pan Chen, Jun Yu, Qian Luo, Jie Li and Wei Wang
    Citation: BMC Gastroenterology 2023 23:382
  30. Previous studies have indicated that HBV pregenome RNA (HBV pgRNA) could predict HBeAg seroconversion among the chronic hapatitis B (CHB) patients treated with pegylated interferon (Peg-IFN) or nucleos(t)ide a...

    Authors: Guangjun Song, Ruifeng Yang, Qian Jin, Juan Liu, Huiying Rao, Bo Feng and Yandi Xie
    Citation: BMC Gastroenterology 2023 23:381
  31. Focal acute pancreatitis is a special type of acute pancreatitis, which diagnosis is based on image showing a focal mass formation in the pancreas. For acute pancreatitis with or without focal inflammatory enl...

    Authors: Mengmeng Ding, Renren Wang, Huawei Xu, Meng Li, Tao Zhou, Yueyue Li, Yanjing Gao and Xiaomeng Gu
    Citation: BMC Gastroenterology 2023 23:380
  32. Ruptured aneurysm is a serious complication of distal pancreatectomy (DP) or pancreatoduodenectomy (PD) that can be life-threatening if not treated promptly. This study aimed to examine the efficacy of a Viaba...

    Authors: Hideki Izumi, Hisamichi Yoshii, Rika Fujino, Shigeya Takeo, Eiji Nomura, Masaya Mukai, Satoshi Suda, Kosuke Tomita, Shunsuke Kamei, Yukihisa Ogawa, Terumitsu Hasebe and Hiroyasu Makuuchi
    Citation: BMC Gastroenterology 2023 23:379
  33. Paediatric inflammatory bowel disease (PIBD) patients require chronic care over the lifespan. Care for these patients is complex, as it is adapted for childrens’ life stages and changing disease activity. Guid...

    Authors: Aletta Boerkoel, Luisa Tischler, Kalina Kaul, Heiko Krause, Ulrike Stentzel, Stefan Schumann, Neeltje van den Berg and Jan de Laffolie
    Citation: BMC Gastroenterology 2023 23:378
  34. Non-alcoholic fatty liver disease (NAFLD) is easily neglected in the non-obese population. TyG index (triglyceride glucose Index) and TG/HDL-c (triglyceride to high-density lipoprotein cholesterol) are new ind...

    Authors: Shuying Li, Li Feng, Jie Ding, Weihong Zhou, Tangbin Yuan and Jiangfeng Mao
    Citation: BMC Gastroenterology 2023 23:376
  35. Natural orifice transluminal endoscopy surgery (NOTES) gastrojejunal anastomosis (GJA) with duodenal exclusion (DE) could be used as a less invasive alternative to surgical gastric bypass. The aim of this stud...

    Authors: S Ouazzani, L Monino, L Beyer-Berjot, E Garnier, S Berdah, M Barthet and JM Gonzalez
    Citation: BMC Gastroenterology 2023 23:375
  36. This paper aimed to assess the clinical efficacy, adverse reactions, and safety of employing PD-1 inhibitors in conjunction with chemotherapy as a treatment strategy for advanced gastric cancer (GC).

    Authors: Xue Huang, Du He, Lin Lai, Jun Chen, Yukun Zhang and Huilin Mao
    Citation: BMC Gastroenterology 2023 23:374
  37. Authors: Yoshiaki Mihara, Masataka Hirasaki, Yosuke Horita, Takashi Fujino, Hisayo Fukushima, Yasuo Kamakura, Kousuke Uranishi, Yasumitsu Hirano, Shomei Ryozawa, Masanori Yasuda, Yoshinori Makino, Satomi Shibazaki and Tetsuya Hamaguchi
    Citation: BMC Gastroenterology 2023 23:373

    The original article was published in BMC Gastroenterology 2023 23:339

  38. Magnetic resonance imaging (MRI) has excellent accuracy in diagnosing preoperative lesions before anal fistula surgery. However, MRI is not good in identifying early recurrent lesions and effective methods for...

    Authors: Hao Xu, Guo-Zhong Xiao, Yi-Hui Zheng, Yuan-Ji Fu, Sheng-Lan Zhong, Dong-Lin Ren, Wen-Ru Li and Hong-Cheng Lin
    Citation: BMC Gastroenterology 2023 23:372
  39. Iatrogenic esophageal perforation (IEP) is a severe adverse event (AE) of upper endoscopy procedures (UEPs) associated with morbidity. Management has shifted from surgery to endotherapy with clip closure (CC),...

    Authors: Eric M. Montminy, Blake Jones, J. Christie Heller and Augustin Attwell
    Citation: BMC Gastroenterology 2023 23:371
  40. The need for pain management is increasing in pediatrics, but the side effects of overuse or abuse of analgesics can be harmful to children’s health and even life-threatening in severe cases.

    Authors: Fangyu Dai, Rensen Zhang, Ruyu Deng, Guoyong Wang, Hongjie Guo and Chunbao Guo
    Citation: BMC Gastroenterology 2023 23:369
  41. Ulcerative colitis (UC) represents a clinically challenging condition characterized by persistent damage to the colonic epithelial mucosa as the principal pathological feature. Polyvinyl alcohol (PVA) solution...

    Authors: Zhiyong Zhang, Lingnan Kong, Ming Lv, Yukuan Yao, Li Gao, Ruchen Zhou, Wenlong Ma and Jing Li
    Citation: BMC Gastroenterology 2023 23:368
  42. It is widely known that muscle mass influences the outcomes of many chronic diseases. Erector spine mass is a convenient parameter obtained from routine abdominal computed tomography (CT). The clinical applica...

    Authors: Chao Zhou, Yuan Liu, Xiaoxiao Liang, Ning Zhang, Tingting He, Jingjing Zhang, Jin Zhang, Shuangnan Fu, Xin Li, Pengcheng Liu, Tianyi Zhang and Man Gong
    Citation: BMC Gastroenterology 2023 23:367

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