Table 1 Mean copy number per cell for the 12 DNA targets tested in esophageal mucosa of chagasic megaesophagus and normal mucosa groups.

FHIT

1.77 ± 0.08

1.78 ± 0.08

1.76 ± 0.08

1.35 ± 0.49

1.75 ± 0.04

1.74 ± 0.04

^ns P = 0.7803

PIK3CA

1.76 ± 0.09

1.78 ± 0.08

1.77 ± 0.07

1.70 ± 0.09

1.78 ± 0.11

1.74 ± 0.01

^ns P = 0.6982

TP63

1.77 ± 0.11

1.78 ± 0.09

1.77 ± 0.09

1.70 ± 0.09

1.78 ± 0.11

1.74 ± 0.01

^ns P = 0.5304

EGFR

1.52 ± 0.12^a

1.45 ± 0.15^b

1.49 ± 0.13^{a, b}

1.60 ± 0.00

1.74 ± 0.01

1.67 ± 0.01

^nsP = 0.3700

FGFR1

1.78 ± 0.01

1.76 ± 0.10

1.77 ± 0.08

1.63 ± 0.01

1.70 ± 0.03

1.67 ± 0.03

^ns P = 0.2200

MYC

1.76 ± 0.09

1.75 ± 0.09

1.76 ± 0.08

1.66 ± 0.01

1.74 ± 0.02

1.70 ± 0.01

^ns P = 0.5396

CDKN2A

1.49 ± 0.08

1.50 ± 0.07

1.50 ± 0.06

1.76 ± 0.14

1.72 ± 0.01

1.74 ± 0.07

* P < 0.0001

YES1

1.67 ± 0.13

1.67 ± 0.12

1.67 ± 0.11

1.70 ± 0.08

1.68 ± 0.13

1.69 ± 0.07

^ns P = 0.8099

NCOA3

1.65 ± 0.11

1.64 ± 0.11

1.64 ± 0.10

1.66 ± 0.11

1.61 ± 0.01

1.64 ± 0.06

^ns P = 0.7656

Centromere 3

1.77 ± 0.08

1.79 ± 0.07

1.77 ± 0.07

1.71 ± 0.07

1.76 ± 0.08

1.74 ± 0.08

^nsP = 0.6638

Centromere 7

1.53 ± 0.12

1.50 ± 0.16

1.52 ± 0.13

1.67 ± 0.01

1.79 ± 0.04

1.73 ± 0.21

^nsP = 0.1235

Centromere 9

1.53 ± 0.09

1.53 ± 0.09

1.53 ± 0.07

1.77 ± 0.15

1.77 ± 0.04

1.77 ± 0.10

* P = 0.0002