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Table 2 Frequencies of cells with loss, normal status and gain in copy numbers of the target in chagasic megaesophagus and normal mucosa groups.

From: Chromosomal imbalances are uncommon in chagasic megaesophagus

  <2 copies per cell 2 copies per cell >2 copies per cell
Target CM NM χ2test CM NM CM NM
FHIT        
N 20 2 P = 10.672ns 2478 144 6 3
% 0.79 1.34   98.96 96.64 0.24 2.04
PIK3CA        
N 898 57 P = 0.000* 1530 139 35 4
% 36.39 28.50   61.99 69.50 1.42 2.00
TP63        
N 885 58 P = 2.579ns 2878 136 37 6
% 23.29 29.00   75.74 68.00 0.97 3.00
EGFR        
N 298 12 P = 1.067ns 3433 187 171 1
% 7.59 6.00   88.03 93.50 4.38 0.50
FGFR1        
N 928 68 P = 4.172ns 2833 121 46 1
% 24.38 34.00   74.41 60.50 1.21 0.50
MYC        
N 918 62 P = 4.812ns 2849 135 33 2
% 24.00 31   75.00 67.50 0.01 1.00
CDKN2A        
N 183 6 P = 17.702 ns 3649 194 68 0
% 4.69 3.00   93.56 97.00 1.74 0.00
YES1        
N 1381 62 P = 2.171ns 2407 136 12 2
% 36.34 31.00   63.34 68.00 0.32 1.00
NCOA3        
N 45 8 P = 3.627ns 2366 130 8 0
% 1.86 5.80   97.81 94.20 0.33 0.00
CEN3        
N 683 54 P = 0.470ns 2510 145 7 1
% 21.0 27.0   78.44 72.5 0.56 0.50
CEP7        
N 1637 56 P = 0.00+* 1509 1143 54 1
% 51.16 28.0   47.16 71.50 1.68 0.50
CEP9        
N 1400 46 P = 0.00+* 1468 154 332 0
% 43.75 23.0   45.87 77.0 10.38 0.00
  1. CM, chagasic megaesophagus; NM, normal mucosa; SD, standard-deviation; Statistical Analysis: t-Student; *, P < 0.05; ns, P > 0.05; a, b, P = 0.008.