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Table 1 Baseline characteristics of patients and controls.

From: Prevalence of genetic polymorphisms in the promoter region of the alpha-1 antitrypsin (SERPINA1) gene in chronic liver disease: a case control study

 

Patients

Controls

p-value

 

(n = 297)

(n = 297)

 

Male (%)

168 (57)

163 (55)

0.74

Mean age (range)

51.4 yrs (19-85)

51.5 yrs (20-85)

0.94

Mean age at onset liver disease (range)

43 yrs (7-82)

  

Cirrhosis (%)

69 (23)

  

Cause of liver disease (%)

   

-HCV

129 (43)

  

-AIH/PBC/PCS

53 (18)

  

-HBV

50 (17)

  

-Alcoholic liver disease

21 (7)

  

-NASH/metabolic

16 (5)

  

-Cryptogenic

13 (4)

  

-Drug induced liver injury

11 (4)

  

-Vascular

4 (1)

  
  1. HCV = hepatitis C virus, AIH/PSC/PBC = autoimmune hepatitis/primary biliary cirrhosis/primary sclerosing cirrhosis, HBV = hepatitis B virus, NASH = non-alcoholic steato hepatitis