Table 5 Characteristics of naive subjects with and without discordance between FibroTest and LSM for the diagnosis of advanced fibrosis
Characteristics | Discordance | Significance | ||||
|---|---|---|---|---|---|---|
No | Yes | Univariate | Multivariate | |||
P | OR | 95%CI | P | |||
Number of subjects | 698 | 68 | ||||
Age at serum, years | 57.0 | 59.7 | 0.04 | 1.02 | 1.00-1.06 | 0.048 |
Male (%) | 349/698 (50%) | 49/68 (72%) | 0.0005 | 2.45 | 1.39-4.30 | 0.002 |
Thoracic fold | 16.4 | 18.4 | 0.03 | 1.05 | 1.01-1.08 | 0.01 |
Operator effect | 299/698 (43%) | 40/68 (59%) | 0.01 | 2.12 | 1.28-2.12 | 0.005 |
Cholesterol (mmol/L) | 5.7 | 5.2 | 0.0002 | 0.58 | 0.44-0.76 | <0.0001 |
Weight (kg) | 69.4 | 73.2 | 0.04 | Not | Included final model | NS |
Waist circumference | 83 | 87 | 0.005 | Not | Included final model | NS |
Body mass index | 24.6 | 25.1 | 0.28 | Not | Included final model | NS |
ALT | 24.7 | 28.2 | 0.007 | Not | Included final model | NS |
Fasting Glucose (mmol/L) | 5.3 | 5.6 | 0.01 | Not | Included final model | NS |
HDL-cholesterol (mmol/L) | 0.61 | 0.55 | 0.002 | Not | Included final model | NS |
Triglycerides (mmol/L) | 1.2 | 1.2 | 0.81 | Not | Included final model | NS |
SteatoTest | 0.31 | 0.36 | 0.04 | Not | Included final model | NS |