Table 1 Levels of serum markers used to formulate the non-invasive fibrosis index

I (Normal)

0.015 ± 0.006

9.27 ± 0.83

6.10 ± 0.10

1.42 ± 0.04

TAA

II (TAA)

0.19 ± 0.017a

28.49 ± 1.32a

3.83 ± 0.17a

0.82 ± 0.02a

III (TAA silymarin)

0.037 ± 0.006ab

13.9 ± 0.82ab

5.67 ± 0.22ab

1.34 ± 0.01ab

IV (TAA then Silymarin)

0.024 ± 0.009b

10.42 ± 0.82b

5.98 ± 0.13b

1.38 ± 0.03b

S. mansoni

V (S. mansoni infection).

0.127 ± 0.019a

22.93 ± 0.52a

4.74 ± 0.22a

1.23 ± 0.02a

VI (PZQ after infection).

0.103 ± 0.019a

22.00 ± 0.63a

4.80 ± 0.23a

1.24 ± 0.03a

VII (Silymarin during infection).

0.054 ± 0.008ab

16.91 ± 1.04ab

5.25 ± 0.18ab

1.33 ± 0.03ab

VIII (Silymarin after infection).

0.065 ± 0.008ab

18.30 ± 0.97ab

5.07 ± 0.11ab

1.31 ± 0.01ab

IX (Silymarin after PZQ).

0.017 ± 0.006b

9.73 ± 0.63b

5.95 ± 0.15b

1.41 ± 0.02b

Ethanol

X (Ethanol).

0.162 ± 0.017a

26.17 ± 1.32a

4.31 ± 0.20a

0.99 ± 0.03a

XI (Silymarin during ethanol intake).

0.028 ± 0.006ab

11.12 ± 1.04ab

5.85 ± 0.23ab

1.34 ± 0.01ab

XII (Silymarin after ethanol intake).

0.022 ± 0.008b

10.19 ± 0.97b

5.95 ± 0.35b

1.40 ± 0.02b