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Table 2 Liver and oxidative stress markers in liver tissue

From: Non-invasive index of liver fibrosis induced by alcohol, thioacetamide and schistosomal infection in mice

Inducer

Group No. (treatment)

HP

Collagen

MDA

 

I (Normal)

14.84 ± 1.24

110.80 ± 9.22

0.83 ± 0.02

TAA

II (TAA)

42.65 ± 3.65a

318.19 ± 27.2a

2.15 ± 0.12a

 

III (TAA+ silymarin)

17.33 ± 1.97ab

129.24 ± 14.66ab

0.99 ± 0.07ab

 

IV (TAA then Silymarin)

16.14 ± 1.43b

122.14 ± 10.70b

0.87 ± 0.04 b

S. mansoni

V (S. mansoni infection).

32.40 ± 2.35a

241.83 ± 17.50a

1.39 ± 0.14a

 

VI (Praziquantel after infection).

31.72 ± 2.68a

236.62 ± 20.02a

1.32 ± 0.05a

 

VII (Silymarin during infection).

19.28 ± 1.35ab

143.84 ± 10.08ab

1.09 ± 0.07a

 

VIII (Silymarin after infection).

21.92 ± 1.54ab

163.51 ± 11.47ab

1.14 ± 0.05a

 

IX (Silymarin after Prazaquantel).

15.94 ± 1.31b

118.88 ± 9.76b

0.85 ± 0.01b

Ethanol

X (Ethanol).

37.96 ± 3.20a

283.19 ± 23.88a

1.74 ± 0.06a

 

XI (Silymarin during ethanol intake).

17.70 ± 1.58ab

132.04 ± 11.79ab

0.95 ± 0.02ab

 

XII (Silymarin after ethanol intake).

15.98 ± 1.82b

119.21 ± 13.55b

0.87 ± 0.03b

  1. HP: hydroxyprolin, TP: total protein, MDA: malondialdehyde.
  2. Small letters (a) and (b) indicate a significant changes of the corresponding group compared to normal and untreated groups, respectively.