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Figure 2 | BMC Gastroenterology

Figure 2

From: Analysis of cell cycle-related proteins in gastric intramucosal differentiated-type cancers based on mucin phenotypes: a novel hypothesis of early gastric carcinogenesis based on mucin phenotype

Figure 2

Frequencies of cell cycle-related protein expressions in gastric, intestinal and mixed phenotypes. Gastric phenotype cancers are characterized by p53 and cyclin A overexpressions. Although the frequency of p27 overexpression between the intestinal phenotype and other phenotypes did not reach statistical difference, this may be characteristic of the intestinal phenotype. Reduction of p21 and accumulation of β-catenin are commonly observed in the 3 phenotypes. Ki-67 positive rate is higher in the gastric phenotype or mixed phenotype than in the intestinal phenotype. Statistical comparisons used Tamhane tests for all 3 phenotypes.

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