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Table 4 Meta-analysis of all seven included RCTs together with two articles only with abstract

From: A meta-analysis for the effect of prophylactic GTN on the incidence of post-ERCP pancreatitis and on the successful rate of cannulation of bile ducts

Trials

Subgroup(N)

Risk ratio (95%) CI

Z

P value

Heterogeneity

     

x2

P

I2,%

The effect of GTN on the primary rate of cannulation

all forms#

7 studies(n = 1233)

1.02 [0.96, 1.07]

0.57

0.57

6.22

0.40

3.6

all forms*

5 studies(n = 900)

0.99 [0.93, 1.06]

0.32

0.75

2.41

0.66

0

sublingual form#

3 studies(n = 587)

1.01 [0.93, 1.09]

0.22

0.83

6.12

0.05

67.3

topical form

2 studies(n = 184)

1.04 [0.91, 1.19]

0.59

0.56

0.00

0.95

0

The effect of GTN on the overall rate of cannulation

all forms#

8 studies(n = 1376)

1.01 [0.99, 1.04]

1.01

0.31

8.87

0.26

21.1

all forms*

7 studies(n = 1294)

1.01 [0.99, 1.04]

1.04

0.30

8.98

0.17

32.3

sublingual form#

3 studies(n = 552)

1.06 [0.98, 1.15]

1.95

0.05

2.91

0.23

31.3

topical form

2 studies(n = 184)

1.01 [0.96, 1.06]

0.45

0.65

0.39

0.53

0

  1. #: analysis with one or both of the two articles only with abstract available
  2. *: analysis without the two articles only with abstract available