Presence of intestinal Mycobacterium avium subspecies paratuberculosis(MAP) DNA is not associated with altered MMP expression in ulcerative colitis

Table 3 Demographical and clinical data of the IBD patient cohort

	UC (n = 49)	CD (n = 14)
Age (years)
- mean +/-SD	39.6 +/- 13.5	32.4 +/- 13.1
- range	19-74	20-68
Sex [male/female (n)]	26/23	7/7
Disease manifestation UC (n)
- rectum	4
- rectosigmoid	19
- including C. descendens (leftsided colitis)	9
- pancolitis	17
Disease manifestation CD (n)
- terminal ileum		2
- terminal ileum + colon		6
- colon only		6
Endoscopic classification ¹ (n)
- mild inflammation	15	4
- moderate inflammation	27	8
- severe inflammation	7	2
Histopathologic examination (n)
- mild disease activity	20	1
- moderate disease activity	23	8
- severe disease activity	6	1
Anti-inflammatory therapy [AIT, (n)] ²
- no AIT	14	1
- AIT	35	13
substance class
- 5-ASA	31	6
- corticosteroids	8	8
- immunomodulators	3	3

¹ Macroscopic classification of the degree of inflammation was adjusted according to the Mayo endoscopic subscore [19].
² Some patients received different substance classes, therefore the summation of patients in the category "substance class" exceeds the number of patients in the category "AIT". 5-ASA: 5-amino salicylic acid and its derivatives, immunomodulators: azathioprine and infliximab.

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