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Table 2 Performance of non-invasive markers for prediction of esophageal/gastric varices

From: Transient elastography for predicting esophageal/gastric varices in children with biliary atresia

 

Splenomegaly

APRI

Fibroscan

Cut-off

-

1.92

12.7

Sensitivity (%)

92

84

84

Specificity (%)

85

83

77

PPV (%)

88

85

81

NPV (%)

91

83

81

Accuracy (%)

89

84

83

LR+

6.15

5.08

4.23

LR-

0.09

0.18

0.19

AUC

-

0.87

0.89

95% CI

0.85-0.99

0.78-0.96

0.80-0.98

  1. APRI, AST-to-platelet ratio index; PPV, positive predictive value; NPV, negative predictive value; LR+, likelihood ratio for positive results; LR-, likelihood ratio for negative results; AUC, area under the curve; CI, confidence interval.