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Table 2 Distribution of selected variables in the BCH, ESCD, ESCC and controls

From: Multi-susceptibility genes associated with the risk of the development stages of esophageal squamous cell cancer in Feicheng County

Feature

BCH

(n = 270)

ESCD

(n = 262)

ESCC

(n = 226)

Controls

(n = 246)

x 2 (P c )

Gender (n,%)

     

   Male

185(68.5)

151 (57.7)

162 (71.7)

125(50.8)

29.062

   Female

85(31.5)

111 (42.3)

64 (28.3)

121(49.2)

(<0.001)

Age(yr) (n,%)

    

   <50

70(26.0)

40(15.3)

38(16.8)

142(57.7)

150.471

   50-

138(51.1)

138(52.7)

102(45.1)

66(26.8)

(<0.001)

   ≥60

62(23.0)

84(32.1)

86(38.1)

38(15.4)

 

School (yr) (n,%)

    

   ≤6

110 (40.9)

148 (56.5)

144 (63.7)

102(41.5)

39.792

   9

129(47.7)

92 (35.1)

72(31.9)

120(48.8)

(<0.001)

   ≥10

31(11.5)

22 (8.4)

10(4.4)

24(9.8)

 

Income per year ($) (n,%)

    

   <150

129(47.7)

134 (51.1)

98 (43.4)

164(66.7)

36.494

   150-

117(43.4)

92(35.1)

94(41.6)

66(26.8)

(<0.001)

   ≥350

24(8.9)

36(13.7)

34(15.0)

16(6.5)

 

Smoking indexa(n,%)

    

   None

109 (40.4)

148 (56.9)

80 (35.4)

148(60.2)

60.087

   <450

63 (23.4)

38(14.6)

36 (15.9)

48(19.5)

(<0.001)

   ≥450

98 (36.2)

74(28.5)

110 (48.7)

50(20.3)

 

Alcohol drinking Statusb(n,%)

    

   None

114 (42.4)

136 (53.1)

76 (33.6)

138(56.1)

68.712

   <100

43(16.0)

44(17.2)

32 (14.2)

62(25.2)

(<0.001)

   ≥100

112(41.6)

76(29.7)

118 (52.2)

46(18.7)

 

Family history of esophagus cancer (n,%)

   

   None

231 (85.5)

2021(77.1)

190(84.1)

222(90.2)

17.027

   yes

39 (14.5)

60(22.9)

36(15.9)

24(9.8)

(<0.001)

  1. a smoking index = cigarette/day × number of smoking years.b alcohol drinking ≥100g/day means heavy drinker. c P : Chi-square test was for proportions among the four groups.
  2. Abbreviations: BCH, Basal cell hyperplasia; ESCD, esophageal squamous cell dysplasia; ESCC, Esophageal Squamous cell cancer.