Mean symptom ratings during a flare in mild-to-moderate UC, as assessed by patients, physicians, and nurses. Patients with mild-to-moderate disease were asked to rate each of the following to describe a typical flare of UC on a continuous rating scale: frequency of stools per day, frequency of blood in stools, and feeling of urgency to go to the bathroom. Physicians and nurses were asked to rate the same choices according to how they would define a typical flare experienced by a mild-to-moderate patient. Ratings were transformed to a 10-point scale; higher scores indicated greater symptom severity. UC, ulcerative colitis. *Based on mild-to-moderate cases only.