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Figure 7 | BMC Gastroenterology

Figure 7

From: Longitudinal fluctuations in PD1 and PD-L1 expression in association with changes in anti-viral immune response in chronic hepatitis B

Figure 7

(A) Co-localization of PD-L1 with CD31 and CD68 is shown by immunofluorescence double staining in liver biopsy specimens of patients with hepatitis B in T4. PD-L1 (red) is co-localized with CD31 (green) positive endothelia cells or CD68 (green) positive Kupffer cells. The 2-color merged panels show co-localization visible (yellow). Original magnification × 200. (B) Co-localization of PD-L1 and CD11c in liver tissue from patients during T3. PD-L1 (red) is co-localized with CD11c (green). The 2-color merged panels show co-localization (yellow). Most CD11c + cells expressed PD-L1. Original magnification × 200. (C) Co-localization of PD-L1 and CD11c in liver tissue from patients in T4. PD-L1 (red) is co-localized with CD11c (green). The 2-color merged panels show co-localization (yellow). Most CD11c + cells did not express PD-L1. Only CD11c + cells in the circle expressed PD-L1. Original magnification × 200.

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