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Table 2 Comparison of laboratory parameters between different patient groups after antiviral treatment

From: Study of the effect of antiviral therapy on homocysteinemia in hepatitis C virus- infected patients

Biochemical Parameters

Groups

Overall

Comparisons between groups

 

Group I Responders (n = 155)

Group II Non-responders (n = 110)

Group III Relapse-cirrhotics (n = 90)

P

I & II

I &III

II & III

Hb (g/dl)

14.56194 ± 1.197414

18.1790909 ± 1.002574251

11.22778 ± 1.300564

<0.0001***

<0.01*

<0.01*

<0.01*

PLT (*100)

237.7032 ± 63.00476

130.724771 ± 36.55282113

122.9111 ± 35.38286

0.6+

-

-

-

TLC

6.129032 ± 1.145968

12.5654545 ± 2.160463608

6.246667 ± 1.324887

<0.0001***

<0.01*

NS

<0.01*

ESR (mm/hr)

19.63226 ± 7.286368

40.6818182 ± 22.31177408

29.93333 ± 10.32592

<0.0001***

<0.01*

<0.01*

<0.01*

ALT1 (U/L)

118.5484 ± 36.21046

76.0727273 ± 23.96354613

102 ± 68.31355

<0.0001***

<0.01*

<0.05*

<0.01*

ALT2 (U/L)

72.77419 ± 17.2674

121.154545 ± 32.52499007

82.44444 ± 56.79178

<0.0001***

<0.01*

NS

<0.01*

ALT3 (U/L)

41.42581 ± 9.053914

181.327273 ± 48.44122687

115.2889 ± 64.24326

<0.0001***

<0.01*

<0.01*

<0.01*

ALP1 (U/L)

336.2516 ± 20.15414

304.045455 ± 12.09623974

349.9111 ± 25.01624

<0.0001***

<0.01*

<0.01*

<0.01*

ALP2 (U/L)

251.6258 ± 24.00545

340.227273 ± 10.83035074

324.8778 ± 24.07938

<0.0001***

<0.01*

<0.01*

<0.01*

ALP3 (U/L)

170.9484 ± 28.92799

380.763636 ± 12.85267778

365.7222 ± 20.64849

<0.0001***

<0.01*

<0.01*

<0.01*

CHOL (mmol/L)

4.643226 ± 0.535738

5.68090909 ± 0.426742613

5.631111 ± 0.777007

<0.0001***

<0.01*

<0.01*

NS

HDL (mmol/L)

1.343226 ± 0.495305

1.29454545 ± 0.297955222

1.357778 ± 0.444436

0.53+

-

-

-

LDL (mmol/L)

3.343226 ± 0.531846

4.25636364 ± 0.408516509

3.153333 ± 1.103233

<0.0001***

<0.01*

NS

<0.01*

TGs (mmol/L)

1.93871 ± 0.567792

2.27454545 ± 0.586614664

2.026667 ± 0.592424

<0.0001***

<0.01*

<0.01*

<0.01*

Hcy (μmol/L)

19.33652 ± 2.434538

44.0485455 ± 9.32508345

56.11422 ± 14.63146

<0.0001***

<0.01*

<0.01*

<0.01*

  1. ***: extremely statistically significant; **: very statistically significant; *: statistically significant; +: statistically non-significant. Hb: hemoglobin; PLT: platelets; TLC: total leukocyte count; ESR: erythrocyte sedimentation rate; ALT1, ALT2 & ALT3: alanine amino transferase levels before, during and after therapy, respectively; ALP1, ALP2 & ALP3: alkaline phosphatase levels before, during and after therapy, respectively; CHOL: cholesterol; HDL: high density lipids; LDL: low density lipids; TGs: triglycerides; Hcy: homocysteine.