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Table 1 Characteristics of the Included Studies

From: Diagnostic accuracy of the aspartate aminotransferase-to-platelet ratio index for the prediction of hepatitis B-related fibrosis: a leading meta-analysis

Author, Year, Country

Study/center

Description

N

Interval Between

Biopsy & APRI

Median/Mean

Age, (% male)

Etiology

Liver Biopsy

Description

Prevalence

Significant

Fibrosis

(Cirrhosis)

QUADAS Score

Chrysanthosa,2006,

Greece [31]

Retrospective

2 centers

205

same day

51 ± 13(74.6%)

HBV

≥ 1.5 cm

42.33%(23.11%)

14

Liu Hongbo,2007,

China [33]

Retrospective

5 centers

444

≤ 1 week

Training group30(71%)

Validation group28(79%)

HBV

≥ 1.0 cm

30.18%(4.50%)

14

Giada Sebastiani,

2007, Italy [10]

Retrospective

2 centers

110

same day

42.6 ± 11.3(72.7%)

HBV

≥ 1.5 cm

68.20%(20%)

14

Beom Kyung Kim

2007, Korea [35]

Retrospective

6 centers

346

same time

34 ± 14(85.3%)

HBV

4 mm

75.4%(22.8%)

14

W.G. Shin,2008,

Korea [32]

Retrospective

2 centers

264

same time

24(87.1%)

HBV

17 mm

53.4%(3.4%)

14

ChenSheng, Lin

2008, China [34]

Retrospective

3 centers

48

Unclear

60.4 ± 11.3(74.2%)

HBV

Unclear

21.70%(40.20%)

12

Ruidan Zheng,

2008, China [36]

Retrospective

3 centers

131

≤ 1 week

34(84.333%)

HBV

≥ 1.0 cm

55.126%(8.897%)

14

Zhongsheng jiang

2008, China [37]

Retrospective

1 center

172

≤ 1 day

35(77.3%)

HBV

≥ 1.5 cm

83%(15%)

14

Sheng-Di Wu,

2010, China [7]

Retrospective

1 center

78

Unclear

32.6 ± 12.3

(84.6%)

HBV

≥ 15 mm

41%(11.5%)

13