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Table 2 Comparison of Data Among IL28B minor allele carriers who achieved SVR or not

From: Effect of laparoscopic splenectomy in patients with Hepatitis C and cirrhosis carrying IL28B minor genotype

 

SVR group (n=4)

Non-SVR group (n=35)

Odds ratio

P value

95% CI

Age ≥60 (yes / no), n

1 / 3

23 / 12

0.17

n.s

0.01 – 1.85

Sex (male / female), n

2 / 2

19 / 16

0.84

n.s

0.11 – 6.67

Hemoglobin level (g/dl), mean ± SD

13.2 ± 0.8

12.9 ± 0.3

-

n.s

-

Platelet count (x104/μl), mean ± SD

7.9 ± 0.9

8.0 ± 0.3

-

n.s

-

Pretreatment viral load (logIU/mL), mean ± SD

6.5 ± 0.4

6.3 ± 0.1

-

n.s

-

HCV genotype (1/2), n

3 / 1

34 / 1

11.3

0.06

0.56 - 230

splenectomy (yes / no), n

3 / 1

8 / 27

10.1

<0.05

0.92-112

ITPA genotype (major/minor), n

3 / 1

26 / 9

1

n.s

0.09 – 11.2

  1. CI; confidence interval, HCV; hepatitis C virus, IL28B; interleukin-28B, ITPA; inosine triphosphate pyrophosphatase, n.s ; not significant, Spx; splenectomy.