Table 1 Baseline Characteristics of study population according to HCV subtype
From: HCV genotype 1a shows a better virological response to antiviral therapy than HCV genotype 1b
Genotype 1a (n = 165) | Genotype 1b (n = 223) | P value | |
|---|---|---|---|
Sex (M/F) | 120/45 | 123/100 | 0.001 |
Age (y) | 45.0 ± 10.6 | 49.0 ± 12.1 | 0.0001 |
BMI (kg/m2) | 24.1 ± 3.2 | 24.0 ± 3.3 | ns |
ALT (IU/ml) | 109.2 ± 68.7 | 101.4 ± 61.2 | ns |
GGT (IU/ml) | 65.1 ± 39.1) | 67.3 ± 54.5 | ns |
Hgb (gr/dL) | 15.2 ± 1.3 | 14.8 ± 1.9 | ns |
HCV-RNA ( log10 IU/ml) | 5.72 ± 0.7 | 5.9 ± 0.5 | 0.006 |
HCV-RNA n (%) | |||
≤ 5 .60 log10 | 52 (32) | 44 (20) | 0.01 |
> 5 .60 log10 | 113 (68) | 179 (80) | 0.01 |
Staging n (%) | |||
≤ S3 | 111 (85) | 151 (79) | ns |
> S3 | 19 (15) | 41 (21) | ns |
Source of Infection n (%) | |||
-BT | 69 (41) | 85 (38) | ns |
-DA | 78 (47) | 92 (41) | ns |
-S | 8 (5) | 15 (7) | ns |
-UN | 11 (7) | 32 (14) | 0.03 |