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Table 3 Factors associated with the likelihood of SVR. Crude and adjusted Odds Ratios (O.R.) derived by multiple logistic regression analysis

From: HCV genotype 1a shows a better virological response to antiviral therapy than HCV genotype 1b

 

Crude O.R. (95% CI)

Adjusted O.R.

(C.I. 95%)

HCV-RNA ≤ 5.6 log10 IU/ml

2.9 (1.8-5.1)

3.2

(2.7-6.9)

≤ S3*

3.8 (2.0-7.3)

3.8

(3.2-7.4)

Subtype 1a

1.9 (1.2-2.9)

1.8

(1.4-4.1)

Age

7.4 (0.9-40.0)

7.0

(1.1-21.2)

< 50

   

> 50

   

BMI

1.7 (1.0-2.8)

1.4

(0.8-2.5)

< 25

   

> 25

   

ALT

1.9 (1.2-3.0)

2.1

(1.3-3.5)

< 100

   

> 100

   

Sex

1.1 (0.7-1.7)

1.3

(0.8-2.2)

RVR

21.0 (11.5-38.3)

3.2

(1.3-7.7)

  1. Legend O:R: odds ratio; BMI: body mass index, ALT: alanine aminotransferase value IU/ml RVR rapid virological response.
  2. *322over 388 patients were submitted to liver biopsy and analyzed for this variable.