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Table 2 Predictors of IBS with values for IgG and IgG4 food antibodies included in the analyses

From: IgG and IgG4 antibodies in subjects with irritable bowel syndrome: a case control study in the general population

 

IgGA

IgGB

IgG4C

OR (95% CI)

p

OR (95% CI)

p

OR (95% CI)

p

HSCL101 (1–4)

3.18 (1.82 to 5.55)

< 0.001

3.32 (1.88 to 5.86)

< 0.001

3.22 (1.84 to 5.62)

< 0.001

Muscle skeletal disease (0–12)

1.14 (1.00 to 1.30)

0.051

1.14 (0.99 to 1.31)

0.063

1.14 (1.00 to 1.30)

0.056

Allergic rhinitis (yes/no)

1.73 (0.99 to 3.02)

0.055

1.72 (0.98 to 3.03)

0.060

1.74 (0.99 to 3.05)

0.053

IgG against FP52, mg/L

1.00 (0.99 to 1.01)

0.83

    

IgG against FP733, mg/L

1.00 (0.96 to 1.04)

0.97

    

IgG against milk, mg/L

  

1.00 (0.98 to 1.01)

0.54

  

IgG against egg, mg/L

  

1.00 (1.00 to 1.01)

0.62

  

IgG against wheat, mg/L

  

0.99 (0.97 to 1.01)

0.32

  

IgG against cod, mg/L

  

1.08 (0.97 to 1.20)

0.15

  

IgG against pork, mg/L

  

1.04 (0.91 to 1.20)

0.57

  

IgG against chicken, mg/L

  

0.94 (0.87 to 1.02)

0.15

  

IgG against beef, mg/L

  

0.94 (0.78 to 1.14)

0.54

  

IgG against brewers’ yeast, mg/L

  

1.01 (0.97 to 1.04)

0.65

  

IgG against Candida albicans, mg/L

  

1.004 (1.000 to 1.008)

0.051

  

IgG4 against milk, mg/L

    

1.00 (0.98 to 1.02)

0.99

IgG4 against egg, mg/L

    

0.99 (0.98 to 1.01)

0.43

IgG4 against wheat, mg/L

    

0.96 (0.91 to 1.02)

0.20

IgG4 against Candida albicans, mg/L

    

1.56 (0.72 to 3.41)

0.26

Dairy products (portions/day)

0.81 (0.68 to 0.96)

0.014

0.80 (0.68 to 0.95)

0.012

0.81 (0.68 to 0.95)

0.011

Sugar (g/day)

1.01 (1.00 to 1.02)

0.043

1.01 (1.00 to 1.02)

0.049

1.01 (1.00 to 1.02)

0.041

  1. All antibodies and other variables with p < 0.1 are shown. Enter logistic regression.
  2. 1Hopkins Symptom Checklist 10 for mood disorders measurement.
  3. 2food panel with the following allergens; milk, egg, cod, wheat, soybean and peanut.
  4. 3food panel with the following meat allergens; chicken, beef, pork and lamb.
  5. Variables included:
  6. A: age, gender, smoking, number of diseases, allergic rhinitis, HSCL10, muscle skeletal disease, IgG against FP5, IgG against FP73, dairy products, vegetables, potatoes, coffee, tea, water, alcohol, omega 3 fatty acids, sugar.
  7. B: age, gender, smoking, number of diseases, allergic rhinitis, HSCL10, muscle skeletal disease, IgG against milk, IgG against egg, IgG against wheat, IgG against cod, IgG against pork, IgG against chicken, IgG against beef, IgG against brewer’s yeast, IgG against Candida albicans, dairy products, vegetables, potatoes, coffee, tea, water, alcohol, omega 3 fatty acids, sugar.
  8. C: age, gender, smoking, number of diseases, allergic rhinitis, HSCL10, muscle skeletal disease, IgG4 against milk, IgG4 against egg, IgG4 against wheat, IgG4 against Candida albicans, dairy products, vegetables, potatoes, coffee, tea, water, alcohol, omega 3 fatty acids, sugar.