Validation of the FIB4 index in a Japanese nonalcoholic fatty liver disease population

BMC Gastroenterology

Table 5 Categorized risk groups for advanced fibrosis according to combined FIB4 index and NAFLD fibrosis score (NFS).

		FIB4 index (cut-off values proposed by Sterling et al.)			Total
		Low cut-off point (< 1.45)	Indeterminate (1.45-3.25)	High cut-off point (> 3.25)
NFS	Low cut-off point (<-1.455)	283 [1 (0.4%)] ^a	42 [4 (9.5%)] ^a	3 [0 (0.0%)] ^a	328 (56.9%) [5 (1.5%)]
	Indeterminate (-1.455-0.676)	53 [5 (9.4%)] ^a	122 [19 (15.6%)] ^b	31 [14 (45.2%)] ^c	206 (35.8%) [38 (18.4%)]
	High cut-off point (> 0.676)	0	17 [4 (23.5%)] ^b	25 [17 (68.0%)] ^c	42 (7.3%) [21 (50.0%)]
Total		336 (58.3%) [6 (1.7%)]	181 (31.4%) [27 (14.9%)]	59 (10.2%) [31 (52.5%)}	576 (100%) [64 (11.1%)]

Total number of patients [stage 3-4 (%)]
Patients were categorized into three groups, "low-risk" (< 10%) ^a, "intermediate-risk" (10-30%) ^b and "high-risk" (> 30%) ^c, based on the combination of FIB4 index and NFS.

ISSN: 1471-230X