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Table 4 Sensitivity and stratified analyses of pooled odds ratio for case–control studies

From: The relationship between urban environment and the inflammatory bowel diseases: a systematic review and meta-analysis

 

Ulcerative colitis

Crohn’s disease

 

Stratified analysis

Meta-regression

Stratified analysis

Meta-regression

 

No. of studies

No. of cases

No. of controls

Pooled OR (95%CI)

Heterogeneity (p-value)

Coef.

P value

No. of studies

No. of cases

No. of controls

Pooled OR (95%CI)

Heterogeneity (p-value)

Coef.

P value

Crude

7

1491

3153

1.06 (0.78, 1.45)

.004

  

9

2028

1002618

1.26 (1.03, 1.53)

.16

  

Time of exposure

Time of data collection

4

1013

2511

1.18 (0.78, 1.80)

.006

-0.32

.42

2

474

1511

1.21 (0.58, 2.50)

.18

0.060

.89

Childhood

3

478

642

0.87 (0.65, 1.17)

.91

  

5

1028

999115

1.18 (0.82, 1.70)

.052

  

0-6 years

       

4

832

998908

1.12 (0.71, 1.77)

.026

0.16

.46

< 16 years

       

1

196

207

1.39 (0.74, 2.60)

NA

  

Source of controls

Population

2

314

487

1.02 (0.66, 1.58)

.16

0.035

.94

3

835

998893

1.40 (1.13, 1.73)

.37

-0.23

.32

Clinic/Hospital

5

1177

2666

1.06 (0.70, 1.60)

.003

  

6

1193

3725

1.09 (0.79, 1.51)

.11

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