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Table 1 Comparison of baseline characteristics (a) between individuals with and without fatty liver at baseline and (b) between individuals with and without incident fatty liver at follow up

From: Predicting incident fatty liver using simple cardio-metabolic risk factors at baseline

 

Baseline fatty liver status (a)

Follow up fatty liver status (b)

 

Absent

Present

(a)

Absent

Present

(b)

   

p value

  

p value

n

2589

988

 

2159

430

 

Age (y)

46.27 ± 8.51

48.08 ± 8.69

<0.0001

46.06 ± 8.57

47.32 ± 8.11

0.005

% Men

1305(50.4%)

800(81.0%)

<0.0001

999 (46.3%)

306 (71.2%)

<0.0001

BMI (kg/m2)

22.94 ± 2.58

26.10 ± 2.42

<0.0001

22.66 ± 2.53

24.33 ± 2.32

<0.0001

Waist

77.00 ± 8.44

87.52 ± 6.68

<0.0001

75.93 ± 8.25

82.36 ± 7.22

<0.0001

Exercise

      

None

817(31.5%)

270(27.3%)

.002

689 (31.9%)

128 (29.8%)

0.81

≤1time/week

359(13.9%)

183(18.5%)

 

297 (13.8%)

62 (14.4%)

 

>1time/week

1413(54.6%)

535(54.1%)

 

1173 (54.3%)

240 (55.8%)

 

% Smoker

      

Never

1821(70.3%)

490(49.6%)

<0.0001

1581 (73.2%)

240 (55.8%)

<0.0001

Past

293(11.3%)

238(24.1%)

 

215 (10.0%)

78 (18.1%)

 

Current

475(18.3%)

260(26.3%)

 

363 (16.8%)

112 (26.0%)

 

Alcohol (gm/day)

5.81 ± 7.07

7.68 ± 7.53

<0.0001

5.37 ± 6.82

8.01 ± 7.84

<0.0001

SBP (mmHg)

115.23 ± 13.82

112.39 ± 15.00

<0.0001

114.60 ± 13.49

118.36 ± 14.97

<0.0001

DBP (mmHg)

74.64 ± 9.89

80.08 ± 10.08

<0.0001

74.06 ± 9.71

77.53 ± 10.25

<0.0001

Triglyceride

(mmol/L)

Median

[IQR]

1.10

[0.80,1.51]

1.80

[1.33,2.44]

<0.0001

1.04

[0.77,1.41]

1.38

[1.04,1.91]

<0.0001

HDL-C (mmol/L)

1.54 ± 0.30

1.40 ± 0.23

<0.0001

1.56 ± 0.31

1.47 ± 0.27

<0.0001

HsCRP (mg/L)

0.82 ± 1.43

1.38 ± 1.75

<0.0001

0.77 ± 1.40

1.03 ± 1.58

<0.0001

Platelets (109/L)

246.14 ± 53.10

235.32 ± 50.57

<0.0001

244.73 ± 52.63

253.16 ± 54.90

0.003

Albumin (g/L)

45.6 ± 2.4

46.7 ± 2.5

<0.0001

45.4 ± 3.0

45.9 ± .2.3

<0.0001

ALT (U/L)

21.44 ± 15.19

38.39 ± 22.02

<0.0001

20.38 ± 11.67

26.69 ± 25.95

<0.0001

AST (U/L)

22.14 ± 7.11

27.99 ± 10.87

<0.0001

21.87 ± 6.93

23.46 ± 7.83

<0.0001

AST/ALT ratio

1.17 ± 0.36

0.82 ± 0.27

<0.0001

1.19 ± 0.36

1.03 ± 0.33

<0.0001

AST/platelet index

9.46 ± 3.97

11.62 ± 5.81

<0.0001

9.38 ± 3.74

9.86 ± 4.95

0.06

Fasting Glucose

(mmol/L)

5.10 ± 0.66

5.55 ± 1.13

<0.0001

5.06 ± 0.56

5.26 ± 1.01

<0.0001

Fasting Insulin (pmol/L)

59.48 ± 18.65

75.39 ± 27.89

<0.0001

58.91 ± 18.18

62.28 ± 20.64

0.002

HOMA-IR

1.95 ± 0.69

2.69 ± 1.16

<0.0001

1.92 ± 0.66

2.10 ± 0.81

<0.0001

MetS, n (%)

135 (5.2%)

293 (29.7%)

<0.0001

92 (4.3%)

43 (10.0%)

<0.0001

  1. Data are presented as mean (SD), except where indicated.