Table 3 Ferritin with cut-off values of 100 mcg/L and 50 mcg/L, and anaemia in the diagnosis of gastrointestinal cancers (in paranthesis are 95% CI)
Gastrointestinal cancer | Colorectal cancer | ||
|---|---|---|---|
Ferritin (cut-off 100 mcg/L) | Sensitivity (%) | 86 (67–95) | 93 (69–100) |
Specificity (%) | 57 (51–62) | 56 (50–62) | |
Positive predictive value (%) | 14 (9–21) | 10 (6–16) | |
Negative predictive value (%) | 98 (94–100) | 99 (96–100) | |
Positive likelihood ratio | 2 | 2.1 | |
Negative likelihood ratio | 0.24 | 0.13 | |
Sensitivity (%) | 59 (39–77) | 64 (39–84) | |
Specificity (%) | 76 (71–81) | 75 (70–80) | |
Ferritin (cut-off 50 mcg/L) | Positive predictive value (%) | 17 (10–27) | 12(6–20) |
Negative predictive value (%) | 96 (92–98) | 98 (95–99) | |
Positive likelihood ratio | 2.5 | 2.6 | |
Negative likelihood ratio | 0.54 | 0.47 | |
Sensitivity (%) | 68 (47–84) | 64 (39–84) | |
Specificity (%) | 51 (45–57) | 50 (44–56) | |
Anaemia | Positive predictive value (%) | 10 (6–16) | 6 (3–11) |
Negative predictive value (%) | 95 (90–98) | 97 (92–99) | |
Positive likelihood ratio | 1.4 | 1.3 | |
Negative likelihood ratio | 0.63 | 0.71 |