Table 1 List of the main hemodynamic parameters of animals in the control and Hepa Wash groups
From: Evaluation of the Hepa Wash®treatment in pigs with acute liver failure
Time [h] | T0 | T4 | T8 | T12 | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Group | Controls (n=5) | Hepa Wash (n=6) | MARS (n=2) | Control (n=5) | Hepa Wash (n=6) | MARS (n=2) | Control (n=5) | Hepa Wash (n=6) | MARS (n=2) | Control (n=2) | Hepa Wash (n=6) | MARS (n=1) |
Cerebral perfusion pressure [mmHg] | 87 ± 10 | 90 ± 4 | 84, 70 | 40 ± 3 | 46 ± 3 | 35, 36 | 24 ± 1 | 34 ± 2* | 21, 34 | 18, 6 | 22 ± 1* | 10 |
Cardiac index [l/min/m2] | 5.06 ± 0.30 | 5.13 ± 0.37 | 4.01, 4.5 | 5.15 ± 0.58 | 5.66 ± 0.50 | 5.65, 6.1 | 3.96 ± 0.17 | 5.36 ± 0.38* | 5.37, 5.71 | 3.58, 2.51 | 4.94 ± 0.33* | - |
ELWI [ml/kg] | 8±1 | 7±1 | 6, 7 | 9±0 | 8±1 | 8, 7 | 9±1 | 7±1 | 7, 7 | 8, 13 | 8±1 | - |
GEDI [ml/m2] | 598±28 | 620±31 | 578, 609 | 571±53 | 619±44 | 602, 579 | 524±58 | 626±28 | 653, 638 | 489, 476 | 622±41 | - |
SVRI [dyn.s.m2.cm-5] | 1291±45 | 1361±200 | 1080, 1307 | 887±66 | 874±85 | 670, 660 | 815±69 | 741±71 | 539, 576 | 570, 762 | 607±49 | - |
Mean Arterial Pressure [mmHg] | 96±9 | 99±4 | 93, 79 | 49±3 | 56±3 | 47, 46 | 38±2 | 48±1* | 36, 48 | 29, 22 | 36±1* | 34 |
Intracranial Pressure [mmHg] | 9.3±0.8 | 9.1±0.9 | 8.2, 9.1 | 9.1±0.8 | 10.4±1.1 | 12.3, 10.4 | 13.6±1.9 | 13.9±2.3 | 14.7, 13.7 | 11.4, 16.4 | 13.9±0.8 | 24.4 |
Intracranial temperature [°C] | 36.8±0.3 | 37.0±0.2 | 38, 37.9 | 36.9±0.2 | 37.4±0.3 | 37.6, 37.7 | 37.2±0.2 | 36.9±0.1 | 37.6, 37,3 | 36.5, 36.6 | 36.9±0.2 | 36.0 |