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Table 1 Serum levels of AFP CEA, CA125 and CA19-9 in the study subjects

From: Combined use of AFP, CEA, CA125 and CAl9-9 improves the sensitivity for the diagnosis of gastric cancer

 

Gastric cancer(n=149)

Benign gastric disease(n=111)

Healthy control(n=124)

Statistic test

Age (Year)

59.1±11.5

52.9±17.4

53.0±9.6

F=10.129, P=0.000

Gender (Male/Female)

115/34

76/35

72/52

χ 2=11.460, P=0.003

AFP (ng/mL)

3.8±16.8

3.3±18.6

2.4±1.3

F=0.332, P=0.718

CEA (ng/mL)

10.5±27.8

1.9±2.8

1.4±0.9

F=11.889, P=0.000

CA125 (U/mL)

20.1±32.7

11.6±17.5

9.9±7.2

F=7.895, P=0.002

CA19-9 (U/mL)

22.8±39.1

11.4±18.7

9.5±4.7

F=10.169, P=0.000

AFP Positive cases (%)

7 (4.7)

1 (0.9)

1 (0.8)

χ 2=4.838, P=0.054

CEA Positive cases (%)

26 (17.4)

2 (1.8)

0 (0.0)

χ 2=38.088, P=0.000

CA125 Positive cases (%)

21(14.1)

7 (6.3)

1 (0.8)

χ 2=18.934, P=0.000

CA19-9 Positive cases (%)

31(20.8)

9 (8.1)

0 (0.0)

χ 2=37.840, P=0.000

Combination Positive Cases (%)

60 (40.3)

14 (12.6)

2 (1.6)

χ 2=74.443, P=0.000