Table 5 Use of optimal boundary values of serum tumor markers for gastric cancer diagnosis

AUC (95% CI)

0.449

0.767

0.589

0.566

0.785

(0.390~

(0.718~

(0.529~

(0.503~

(0.739~

0.509)

0.816)

0.648)

0.630)

0.832)

Positive boundary value

≥7.29 ng/mL

≥2.24 ng/mL

≥22.90 U/mL

≥19.53 U/mL

≥0.419

Sensitivity (%)

4.7

58.4

19.5

30.2

47.7

Specificity (%)

99.1

83.4

95.7

92.8

91.1

Accuracy (%)

62.5

73.7

66.1

68.5

74.2

Positive/negative predictive value (%)

77.8/62.1

69.0/76.0

74.4/65.2

72.6/67.7

77.2/73.3

Positive/Negative likelihood ratio

5.52/0.96

3.52/0.50

4.57/0.84

4.18/0.75

5.33/0.58