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Table 2 Cox regression analysis of factors potentially related to overall survival

From: Overall survival in response to sorafenib versus radiotherapy in unresectable hepatocellular carcinoma with major portal vein tumor thrombosis: propensity score analysis

 

Log-rank test

Cox

Covariates

n

Pvalue

Pvalue

HR

95% CI

Age (≥70/<70 y)

33/23

0.355

   

Sex (male/female)

42/14

0.424

   

HCV (present/absent)

34/22

0.58

   

*Main trunk (present/absent)

16/40

0.612

   

Extrahepatic spread (present/absent)

5/51

0.278

   

Previous treatments (present/absent)

38/18

0.546

   

AFP ≥ 100 (ng/dL)

28/28

0.073

   

DCP ≥ 1000 (mAU/mL)

27

0.066

0.024

1

 

<1000

29

  

0.508

0.282, 0.915

Sorafenib

28

0.002

0.007

1

 

RT

28

  

0.434

0.235, 0.779

  1. Abbreviations: HCV hepatitis C virus, AFP α-fetoprotein, DCP des-γ-carboxy prothrombin, RT radiotherapy, HR hazard ratio, CI confidence interval.
  2. *Portal invasion to the main trunk.