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Table 3 Association between variable duration of PPI exposure and TB infection/activation

From: Acid suppressive agents and risk of Mycobacterium Tuberculosis: case–control study

Exposure

Case (%) n = 6541

Control (%) n = 65410

Crude OR

Adjusted OR

3 months

    

Non user

6368(97.36)

64687(98.89)

1

1

User

173(2.64)

723(1.11)

2.43(2.06-2.88)

1.63(1.62-1.63)

6 months

    

Non user

6306(96.41)

64276(98.27)

1

1

User

235(3.59)

1134(1.73)

2.11(1.83-2.44)

1.29(1.29-1.30)

12 months

    

Non user

6221(95.11)

63575(97.19)

1

1

User

320(4.89)

1835(2.81)

1.78(1.58-2.01)

0.99(0.99-1.01)

24 months

    

Non user

6103(93.30)

62519(95.58)

1

1

User

438(6.70)

2891(4.42)

1.55(1.40-1.72)

0.90(0.89-0.90)

  1. Abbreviations: OR, odds ratio. †Adjusted for socioeconomic status, congestive heart failure, coronary heart disease, chronic pulmonary disease, diabetes mellitus, end stage renal disease, liver cirrhosis, alcohol abuse, peptic ulcer disease, reflux esophagitis, gastrectomy, HIV, connective tissue disease, malignant neoplasm, organ transplantation.