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Table 4 Association between variable duration of H 2 RA exposure and TB infection/activation

From: Acid suppressive agents and risk of Mycobacterium Tuberculosis: case–control study

Exposure

Case (%) n=6541

Control (%) n=65410

Crude OR

Adjusted OR

3 months

    

Non user

6203(94.83)

63582(97.21)

1

1

User

338(5.17)

1828(2.79)

1.90(1.68-2.14)

1.51(1.50-1.52)

6 months

    

Non user

6073(92.85)

62528(95.59)

1

1

User

468(7.15)

2882(4.41)

1.67(1.51-1.85)

1.29(1.28-1.29)

12 months

    

Non user

5847(89.39)

60678(92.77)

1

1

User

694(10.61)

4732(7.23)

1.52(1.40-1.66)

1.15(1.14-1.15)

24 months

    

Non user

5549(84.83)

57998(88.67)

1

1

User

992(15.17)

7412(11.33)

1.40(1.30-1.50)

1.06(1.05-1.06)

  1. Abbreviations: OR, odds ratio. †Adjusted for socioeconomic status, congestive heart failure, coronary heart disease, chronic pulmonary disease, diabetes mellitus, end stage renal disease, liver cirrhosis, alcohol abuse, peptic ulcer disease, reflux esophagitis, gastrectomy, HIV, connective tissue disease, malignant neoplasm, organ transplantation.