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Table 1 Symptoms and endoscopic appearances in controls and inflammatory bowel disease

From: Paneth cell metaplasia in newly diagnosed inflammatory bowel disease in children

 

Control

UC

CD

N

14

13

15

Sex (M/F)

10/4

6/7

5/10

Age range (median)

6-16 (12.5)

6-15 (14)

7-16 (13)

Symptoms: n (%)

Diarrhoea

9 (64)

8 (62)

8 (53)

Abdominal pain

9 (64)

4 (31)

7 (47)

Rectal bleeding

6 (43)

10 (77)

6 (40)

Weight loss

4 (29)

6 (46)

2 (13)

Treatment prior to diagnosis: n (%)

Antiinflammatories

2 (14)

7 (54)*

7 (47)

Infliximab

0

4 (31)*

0

Immunosuppressants

0

6 (46)†

1 (7)

Endoscopic appearance: n (%)

Abnormal

1 (7)‡

13 (100)§

15 (100)§

Terminal ileitis

1 (7)‡

0

5 (33)

Extensive colitis

0

7 (54)†

3 (20)

Discontinuous colitis

1 (7)‡

1 (8)

7 (47)*

Left-sided colitis only

0

5 (38)*

0

 

Recto-sigmoid colitis only

0

2 (15)

0

  1. *P < 0.05 (chi-squared) compared to controls.
  2. †P < 0.005 compared to controls.
  3. ‡Histology showed lymphonodular hyperplasia.
  4. §P < 0.00001 compared to controls.