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Figure 4 | BMC Gastroenterology

Figure 4

From: High glucose increases LPS-induced DC apoptosis through modulation of ERK1/2, AKT and Bax/Bcl-2

Figure 4

Effects of glucose on the expression of apoptosis related factors in vitro. (A) Effects of glucose on the protein expression of AKT, ERK, Bax and Bcl-2 in DCs treated with LPS for different periods of time. At high glucose concentrations at 24 h LPS stimulation, the protein expression of AKT, ERK and Bcl-2 decreased, while BAX increased. These effects were not evident in cells treated with LPS for 15 min and 6 h. Actin is internal control. Figure 5.B is the statistical chart. Gray values of target bands were divided by Actin to obtain normalized data. #p < 0.05 vs. control mice.

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