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Table 1 The vacA, iceA, cagA and cagE status of H. pylori strains and clinical outcome

From: Analysis of antimicrobial susceptibility and virulence factors in Helicobacter pyloriclinical isolates

 

Clinical Outcome

Genotype

PUD n (%)

NUD n (%)

GERD n (%)

Total n (%)

vacA

    

   s1

57 (78)*

25 (54)

4 (21)

86 (62)

   s2

16 (22)

21 (46)

15 (79)**

52 (38)

   m1

27 (37)

11 (24)

3 (16)

41 (30)

   m2

46 (63)

35 (76)

16 (84)

97 (70)

   s1m1

27 (37)

11 (24)

3 (16)

41 (30)

   s1m2

30 (41)*

14 (30)

1 (5)

45 (32)

   s2m2

16 (22)

21 (46)

15 (79)**

52 (38)

iceA

    

   iceA1

12 (16)

6 (13)

3 (16)

21 (15)

   iceA2

55 (75)

32 (70)

15 (79)

102 (74)

   iceA -

6 (9)

8 (17)

1 (5)

15 (11)

cagA

    

   cagA +

55 (75)*

25 (54)

9 (47)

89 (65)

   cagA -

18 (25)

21 (46)

10 (53)

49 (35)

cagE

    

   cagE +

60 (82)

39 (85)

17 (90)

116 (84)

   cagE -

13 (13)

6 (15)

2 (10)

22 (16)

  1. * vacA s1 (χ2 = 14.3; p = 0.0002) s1m2 (χ2 = 15.67; p = 0.0004) cagA (χ2 = 7.954; p = 0.0048). ** s2m2 (χ2 = 16.89; p = 0.0002)