Skip to main content

Table 1 The vacA, iceA, cagA and cagE status of H. pylori strains and clinical outcome

From: Analysis of antimicrobial susceptibility and virulence factors in Helicobacter pyloriclinical isolates

  Clinical Outcome
Genotype PUD n (%) NUD n (%) GERD n (%) Total n (%)
vacA     
   s1 57 (78)* 25 (54) 4 (21) 86 (62)
   s2 16 (22) 21 (46) 15 (79)** 52 (38)
   m1 27 (37) 11 (24) 3 (16) 41 (30)
   m2 46 (63) 35 (76) 16 (84) 97 (70)
   s1m1 27 (37) 11 (24) 3 (16) 41 (30)
   s1m2 30 (41)* 14 (30) 1 (5) 45 (32)
   s2m2 16 (22) 21 (46) 15 (79)** 52 (38)
iceA     
   iceA1 12 (16) 6 (13) 3 (16) 21 (15)
   iceA2 55 (75) 32 (70) 15 (79) 102 (74)
   iceA - 6 (9) 8 (17) 1 (5) 15 (11)
cagA     
   cagA + 55 (75)* 25 (54) 9 (47) 89 (65)
   cagA - 18 (25) 21 (46) 10 (53) 49 (35)
cagE     
   cagE + 60 (82) 39 (85) 17 (90) 116 (84)
   cagE - 13 (13) 6 (15) 2 (10) 22 (16)
  1. * vacA s1 (χ2 = 14.3; p = 0.0002) s1m2 (χ2 = 15.67; p = 0.0004) cagA2 = 7.954; p = 0.0048). ** s2m2 (χ2 = 16.89; p = 0.0002)
\