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Table 3 Uunivariate analysis of the relationship between survival and the tested markers

From: Cyclin A and cyclin D1 as significant prognostic markers in colorectal cancer patients

PredictiveVariables

Median Survival

HR

CI

P

Ki-67

   <11.5

36

   

   ≥11.5

32

1.826

0.636 – 5.243

0.26

Cyclin D1

   <6.1

35

   

   ≥6.1

18

7.246

1.007 – 45.150

0.03*

Histone H3

   <8.2

35

   

   ≥8.2

29

4.639

0.854 – 25.196

0.07

Cyclin A

   <10.5

35

   

   ≥10.5

15

7.820

1.017 – 60.122

0.02*

Histological grade

   Low

38

   

   High

10

7.331

2.696 – 19.940

0.0001*

Lymph node

   Negative

38

   

   Positive

15

6.826

1.973 – 23.621

0.002*

Stage

   I, II, III

38

   

   IV

12

6.378

1.842 – 22.083

0.001*

Tumor size (cm)

   <5.0

35

   

   ≥5.0

13

4.835

1.386 – 16.868

0.01*

Depth of invasion

   T1, T2

36

   

   T3, T4

20

7.759

1.024 – 58.789

0.04*

Age (years)

   <50

38

   

   ≥50

28

2.802

0.988 – 7.943

0.0526

Sex

   Male

38

   

   Female

36

0.696

00.274 – 1.766

0.4449

  1. * p. value < 0.05 (significant)
  2. HR: Hazard Ratio
  3. CI: 95% confidence Interval