From: Cyclin A and cyclin D1 as significant prognostic markers in colorectal cancer patients
PredictiveVariables | Median Survival | HR | CI | P |
---|---|---|---|---|
Ki-67 | ||||
   <11.5 | 36 |  |  |  |
   ≥11.5 | 32 | 1.826 | 0.636 – 5.243 | 0.26 |
Cyclin D1 | ||||
   <6.1 | 35 |  |  |  |
   ≥6.1 | 18 | 7.246 | 1.007 – 45.150 | 0.03* |
Histone H3 | ||||
   <8.2 | 35 |  |  |  |
   ≥8.2 | 29 | 4.639 | 0.854 – 25.196 | 0.07 |
Cyclin A | ||||
   <10.5 | 35 |  |  |  |
   ≥10.5 | 15 | 7.820 | 1.017 – 60.122 | 0.02* |
Histological grade | ||||
   Low | 38 |  |  |  |
   High | 10 | 7.331 | 2.696 – 19.940 | 0.0001* |
Lymph node | ||||
   Negative | 38 |  |  |  |
   Positive | 15 | 6.826 | 1.973 – 23.621 | 0.002* |
Stage | ||||
   I, II, III | 38 |  |  |  |
   IV | 12 | 6.378 | 1.842 – 22.083 | 0.001* |
Tumor size (cm) | ||||
   <5.0 | 35 |  |  |  |
   ≥5.0 | 13 | 4.835 | 1.386 – 16.868 | 0.01* |
Depth of invasion | ||||
   T1, T2 | 36 |  |  |  |
   T3, T4 | 20 | 7.759 | 1.024 – 58.789 | 0.04* |
Age (years) | ||||
   <50 | 38 |  |  |  |
   ≥50 | 28 | 2.802 | 0.988 – 7.943 | 0.0526 |
Sex | ||||
   Male | 38 |  |  |  |
   Female | 36 | 0.696 | 00.274 – 1.766 | 0.4449 |