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Table 4 Multivariate analysis ofthe relationship between survival and thetested markers

From: Cyclin A and cyclin D1 as significant prognostic markers in colorectal cancer patients

PredictiveVariables

HR

CI

P

Cyclin D1

10.864

1.055 – 86.250

0.03*

   (baseline < 6.1)

-

-

-

Cyclin A

13.886

1.012 – 190.579

0.0490*

   (baseline < 10.5)

-

-

-

Positive Lymph node metastasis

3.921

1.057 – 14.472

0.0410*

Stage IV

3.411

1.048 – 12.083

0.03*

Depth of invasion

   T3, T4

5.408

0.449 – 65.080

0.1836

Age (years)

≥50

1.996

0.678 – 5.878

0.2310

Sex

0.910

0.315 – 2.358

0.8453

  1. p. value < 0.05 (significant)
  2. HR: Hazard Ratio
  3. CI: 95% confidence Interval