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Table 1 Level of Hyaluronate in subgroup of chronic hepatitis B comparing to normal control

From: Serum hyaluronate as a non-invasive marker of hepatic fibrosis and inflammation in HBeAg-negative chronic hepatitis B

Patient Groups

Subgroups

n

Mean ± SD

P value*

Normal control

 

28

20.4 ± 15.4

 

Chronic hepatitis B subgroups (degree of fibrosis)

Stage 0–2

54

24.7 ± 31.9

0.69

 

Stage 3–5

11

309.7 ± 143.5

<0.001

Chronic hepatitis B subgroups (degree of inflammation)

Grade 0–8

54

39.6 ± 74.2

0.10

 

Grade ≥ 9

11

236.5 ± 188.7

0.003

  1. *Statistical difference between serum hyaluronate of different groups compared with normal controls.