Table 1 Serum cytokine levels during induction of experimental pancreatitis in R122H-trypsinogen transgenic mice and controls:
From: Characterisation of a transgenic mouse expressing R122H human cationic trypsinogen
untreated | 8 h | 24 h | 48 h | ||||||
|---|---|---|---|---|---|---|---|---|---|
cytokines (pg/ml) | R122H | control | R122H | control | R122H | control | R122H | control | |
MCP-1 | mean | ND | ND | 242,0 | 279,0 | 137,0 | 84,0 | 75,0 | 72,0 |
SD | 137,0 | 91,0 | 77,0 | 26,0 | 42,0 | 30,0 | |||
Il-6 | mean | ND | ND | 60,0 | 74,0 | 6,0 | 9,0 | 6,0 | 4,0 |
SD | 56,0 | 76,0 | 3,0 | 17,0 | 6,0 | 3,0 | |||
Il-10 | mean | ND | ND | 5,0 | 6,0 | 3,0 | 2,0 | 4,0 | 2,0 |
SD | 2,0 | 5,0 | 1,0 | 0,0 | 4,0 | 0,0 | |||
Il-12p70 | mean | ND | ND | 15,0 | 18,0 | 7,0 | 15,0 | 8,0 | 20,0 |
SD | 11,0 | 13,0 | 1,0 | 16,0 | 5,0 | 16,0 | |||
TNF | mean | ND | ND | 10,0 | 10,0 | 8,0 | 5,0 | 9,0 | 7,0 |
SD | 1,0 | 2,0 | 1,0 | 3,0 | 5,0 | 3,0 | |||
IFN-γ | mean | ND | ND | 0,5 | 0,5 | 0,5 | 0,5 | 0,5 | 0,5 |
SD | 0,0 | 0,0 | 0,0 | 0,0 | 0,0 | 0,0 | |||