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Table 4 Major side effects observed during the intravenous and oral phases of CsA administration

From: Colectomy rate in steroid-refractory colitis initially responsive to cyclosporin: a long-term retrospective cohort study

Adverse event

Outcome

N (%)

Treatment Phase

Pulmonary Embolism

Death

1 (2.5%)

Intravenous

>33% ↑ creatinine

Dose maintained

7 (17%)

Oral

2 × creatinine

Dose reduced

1 (2.5%)

Oral

Biliary sludge

Drug discontinued

2 (5%)

Intravenous

↑ liver function tests

Dose maintained

2 (5%)

Intravenous

Seizures

Dose maintained

1 (2.5%)

Oral