Skip to main content

Table 3 The expression of GATA-4 and GATA-6 in different cell types of the gastrointestinal mucosa on the basis of conventional and double immunohistochemistry

From: Transcription factors GATA-4 and GATA-6 in normal and neoplastic human gastrointestinal mucosa

Tissue

Cell type

GATA-4

GATA-6

Stomach

   

Corpus

   
 

Surface epithelial cells

++

++

 

Neck cells

+++

++

 

Parietal cells

+++

++

 

Neuroendocrine cells

-

-

Antrum

   
 

Surface epithelial cells

++

+

 

Neck cells

+++

++

 

Glandular cells

++

+++

 

Neuroendocrine cells

-

-

Duodenum

   
 

Villus enterocytes

+++

++

 

Crypt enterocytes

++

+++

 

Neuroendocrine cells

-

-

 

Goblet cells

-

+

 

Paneth cells

-

++

Colon

   
 

Surface colonocytes

-

+

 

Crypt cells

-

+++

 

Goblet cells

-

++

 

Neuroendocrine cells

-

-

  1. The expression patterns based on the number of positive cells detected:
  2. - no expression,
  3. + low expression; <20% of the cells positive
  4. ++ moderate expression; 20–60% of the cells positive
  5. +++ abundant expression; >60% of the cells positive