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Table 1 Distributions and odds ratios of ESCC associated with selected demographic characteristics and substance uses

From: Polymorphism in COX-2 modifies the inverse association between Helicobacter pyloriseropositivity and esophageal squamous cell carcinoma risk in Taiwan: a case control study

Factor/Category

Cases

Controls

 
 

No. (%)

No. (%)

AOR1 (95% CI)

Total No.

180

194

 

Anatomic subsite of the esophagus

   

   Upper 1/3

39 (22)

  

   Middle 1/3

83 (46)

  

   Lower 1/3

58 (32)

  

Age (years)

   

   <50

63 (35)

70 (36)

1.0

   51–60

36 (20)

58 (30)

0.7 (0.4 – 1.2)

   61–70

45 (25)

36 (18)

1.4 (0.8 – 2.4)

   >70

36 (20)

30 (16)

1.3 (0.7 – 2.4)

Gender

   

   Female

5 (3)

7 (4)

1.0

   Male

175 (97)

187 (96)

1.3 (0.4 – 4.2)

Ethnicity

   

   Fukienese

138 (77)

152 (78)

1.0

   Aborigines

31 (17)

28 (15)

1.2 (0.7 – 2.1)

   Others

11 (6)

14 (7)

0.9 (0.4 – 2.0)

Education level (years)

   

   <7

94 (52)

51 (26)

1.0

   7–12

77 (43)

86 (44)

0.7 (0.4 – 1.4)

   >12

9 (5)

57 (30)

0.2 (0.1 – 0.6)

   p for trend

  

0.001

Tobacco smoking (pack-years)2

   

   No

14 (8)

101 (52)

1.0

   1–20

37 (20)

26 (13)

8.7 (3.2 – 23.6)

   >20

129 (72)

67 (35)

7.7 (3.4 – 17.7)

   p for trend

  

<0.001

Alcohol drinking (drink-years)2

   

   No

36 (20)

130 (67)

1.0

   1–40

44 (24)

34 (18)

3.0 (1.4 – 6.4)

   >40

100 (56)

30 (15)

7.2 (3.6 – 14.7)

   p for trend

  

<0.001

Betel quid chewing (pack-years)2

   

   No

82 (46)

175 (90)

1.0

   1–20

26 (15)

7 (4)

3.9 (1.4 – 10.8)

   >20

69 (39)

12 (6)

5.6 (2.5 – 12.5)

   p for trend

  

<0.001

  1. 1 Odds ratios were adjusted for covariates in the table.
  2. 2One drink corresponds to 15.75-g of alcohol; one smoked pack and chewed pack correspond to 20-cigarettes and 10-betel quids, respectively.