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Table 1 Abnormal values and values within normal ranges of serum anti-OmpC IgA (>25U/mL vs. <20U/mL), anti-GP2 IgG (>20U/mL vs. <15U/mL) and anti-GP2 IgA (>20U/mL vs. <15U/mL) in controls, CD patients and UC patients

From: Anti-Outer membrane protein C and anti-glycoprotein 2 antibodies in inflammatory bowel disease and their association with complicated forms of Crohn’s disease

 

controls

CD

UC

Anti-OmpC IgA >25U/mL

8/45 (18%)

53/86 (62%)

13/25 (52%)

Anti-OmpC IgA <20U/mL

26/45 (58%)

22/86 (26%)

6/25 (24%)

Anti-GP2 IgG >20U/mL

1/45 (2%)

27/86 (31%)

4/25 (16%)

Anti-GP2 IgG <15U/mL

42/45 (93%)

49/86 (57%)

21/25 (84%)

Anti-GP2 IgA >20U/mL

8/45 (18%)

43/86 (50%)

2/25 (8%)

Anti-GP2 IgA <15U/mL

33/45 (73%)

35/86 (41%)

21/25 (84%)

Sens/Spec/NPV/PPV of anti-OmpC IgA [%]

 

71/76/54/87

68/76/81/62

Sens/Spec/NPV/PPV of anti-GP2 IgG [%]

 

36/98/47/96

16/98/67/80

Sens/Spec/NPV/PPV of anti-GP2 IgA [%]

 

55/80/49/84

9/80/61/20

  1. Sens: sensitivity, spec: specificity, NPV: negative predictive value, PPV: positive predictive value.