From: High-saturate-fat diet delays initiation of diethylnitrosamine-induced hepatocellular carcinoma
Week | Group | n | Body weight (g) | Body length (cm) | BMI (g/cm 2) | TC (mmol/L) | TG (mmol/L) | HDL-C (mmol/L) | LDL-C (mmol/L) | ALT (U/L) | AST (U/L) | ALB (g/L) |
---|---|---|---|---|---|---|---|---|---|---|---|---|
10 | NCD | 8 | 379.00 ± 27.83 | 24.13 ± 0.64 | 0.62 ± 0.05 | 1.47 ± 0.17 | 0.17 ± 0.05 | 1.01 ± 0.13 | 0.89 ± 0.09 | 42.38 ± 7.76 | 133.75 ± 22.30 | 35.24 ± 1.13 |
HFD | 8 | 486.88 ± 34.50 | 26.55 ± 0.69 | 0.66 ± 0.03 | 2.13 ± 0.50 | 0.38 ± 0.34 | 1.45 ± 0.25# | 1.39 ± 0.36# | 48.38 ± 14.29 | 172.63 ± 59.49 | 36.18 ± 2.20 | |
NCD + DEN | 7 | 276.9 ± 40.8^& | 23.79 ± 1.19 | 0.49 ± 0.05^^&& | 2.26 ± 0.37^ | 0.47 ± 0.18^ | 1.17 ± 0.35 | 1.32 ± 0.25^ | 170.01 ± 77.55^& | 364.17 ± 261.10 | 36.16 ± 2.34 | |
HFD + DEN | 7 | 363.13 ± 21.91▲▲ $$ | 25.14 ± 0.75▲▲ | 0.57 ± 0.03▲▲$$ | 4.05 ± 1.41▲ | 0.54 ± 0.22 | 2.27 ± 0.48▲▲** | 2.51 ± 1.00▲** | 144.90 ± 22.83**$$ | 187.74 ± 17.89 | 38.96 ± 1.29▲*$ | |
12 | NCD | 8 | 429.50 ± 19.32 | 25.81 ± 0.70 | 0.65 ± 0.03 | 1.58 ± 0.14 | 0.35 ± 0.15 | 1.13 ± 0.15 | 1.02 ± 0.10 | 36.63 ± 18.12 | 131.75 ± 28.74 | 37.25 ± 2.31 |
HFD | 8 | 531.63 ± 36.62 | 27.53 ± 0.44 | 0.70 ± 0.04 | 2.52 ± 0.55# | 0.30 ± 0.11 | 1.82 ± 0.30## | 1.76 ± 0.42# | 166.38 ± 72.26## | 235.00 ± 58.89## | 36.95 ± 2.59 | |
NCD + DEN | 7 | 289.9 ± 65.6^^&& | 23.71 ± 2.06 | 0.51 ± 0.04^^&& | 2.55 ± 0.40^ | 0.46 ± 0.13 | 1.32 ± 0.15 | 1.54 ± 0.18^ | 118.64 ± 20.55^^ | 258.71 ± 48.22^^ | 34.57 ± 3.31 | |
HFD + DEN | 7 | 384.3 ± 28.9▲▲$$ | 25.43 ± 0.53 | 0.59 ± 0.04▲▲$$ | 4.64 ± 0.79▲▲** | 0.59 ± 0.14*$ | 2.77 ± 0.23▲▲** | 2.88 ± 0.56▲▲** | 149.69 ± 35.13** | 272.72 ± 102.56** | 38.90 ± 1.17▲ | |
14 | NCD | 8 | 442.20 ± 49.66 | 26.00 ± 0.91 | 0.66 ± 0.08 | 1.75 ± 0.16 | 0.28 ± 0.18 | 1.12 ± 0.16 | 1.09 ± 0.10 | 53.00 ± 9.62 | 148.56 ± 27.05 | 37.15 ± 1.71 |
HFD | 8 | 571.1 ± 36.58## | 27.25 ± 0.75# | 0.77 ± 0.03# | 2.90 ± 0.63# | 0.39 ± 0.14 | 1.93 ± 0.31## | 2.62 ± 0.63## | 139.10 ± 63.72# | 260.00 ± 90.15# | 36.90 ± 0.91 | |
NCD + DEN | 9 | 285.72 ± 53.95^^&& | 23.94 ± 1.51^^ | 0.50 ± 0.05^^&& | 3.16 ± 0.63^^ | 0.63 ± 0.23^ | 1.61 ± 0.36 | 1.77 ± 0.37^^& | 162.03 ± 34.72^^ | 365.11 ± 70.68^^ | 36.89 ± 3.07 | |
HFD + DEN | 10 | 386.26 ± 47.71▲▲ $$ | 25.75 ± 0.98▲▲ | 0.58 ± 0.04▲▲$$ | 4.85 ± 0.95▲▲**$$ | 0.56 ± 0.20* | 2.65 ± 0.25▲▲**$ | 3.04 ± 0.69▲▲** | 151.86 ± 23.54** | 248.90 ± 68.52▲▲* | 40.00 ± 1.96▲*$ |