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Table 3 High-saturate-fat diet delayed DEN-induced HCC formation (week 14)

From: High-saturate-fat diet delays initiation of diethylnitrosamine-induced hepatocellular carcinoma

Group

Differentiation

Total no. of tumour nodules/rat

No. of rats with tumour nodules ≥5 mM

Average tumour nodules (mm 3)

High

Low

NCD + DEN

1

8

15.33 ± 6.32

2.33 ± 1.32

3196.86 ± 7772.85

HFD + DEN

4

6

7.80 ± 4.37**

1.20 ± 0.79*

513.34 ± 1132.90**

  1. NCD: normal chow diet; HFD: high saturate fat diet; DEN: diethylinitrosamine.
  2. HFD + DEN vs NCD + DEN: *P < 0.05, **P < 0.01.