Figure 2

Dose–response Curves of AS-19 administration. Rate of liver regeneration at 24 h after 60-70% partial hepatectomy as evaluated by [³H]-thymidine incorporation into hepatic DNA in rats having administered SB-269970 hydrochloride (2 mg/kg bodyweight) 16 h after partial hepatectomy (group C) and SB-258719 (4 mg/kg bodyweight) 16 h after partial hepatectomy (group E) and different doses of AS-19 (1, 2, 5, 7.5 and 10 mg/kg body weight) intraperitoneally at 16.5 h after partial hepatectomy. Results represent the findings from at least five rats. Values are expressed as means ± SE.