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Figure 5 | BMC Gastroenterology

Figure 5

From: Effect of 5-HT7receptor blockade on liver regeneration after 60-70% partial hepatectomy

Figure 5

Liver regeneration as evaluated by [ 3 H]-thymidine incorporation into hepatic DNA in 60-70% partially hepatectomized rats and AS-19. Time course of liver regeneration as evaluated by [3H]-thymidine incorporation into DNA in 60-70% partially hepatectomized rats having received intraperitoneally saline (group A) or SB-269970 hydrochloride (2 mg/kg bodyweight) 16 h after partial hepatectomy (group C) or SB-269970 hydrochloride (2 mg/kg bodyweight) followed by intraperitoneal administration of AS-19 (10 mg/kg bodyweight) 16.5 h after partial hepatectomy (group F). Results represent the findings from at least five rats killed at 8, 18, 20, 24, 32, 40, 48, 60 and 72 h (group A) and at 18, 20, 24, 32, 40, 48, 60 and 72 h (groups C and F). Values are expressed as means ± SE. DNA group C vs group F; P < 0.001: 18–48 h.

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