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Table 1 Hazard ratios for uncomplicated peptic ulcer disease associated with factors assessed at the start date (cohort analysis)

From: Risk of uncomplicated peptic ulcer disease in a cohort of new users of low-dose acetylsalicylic acid for secondary prevention of cardiovascular events

 

Adjusted HR (95% CI) a

Sex

  Male

1 (-)

  Female

1.19 (0.95-1.50)

Age at start date, years

  50-59

1 (-)

  60-69

1.08 (0.79-1.47)

  70-79

1.26 (0.92-1.73)

  80-84

1.69 (1.05-2.74)

Year of start date

  2000-2001

1 (-)

  2002-2003

1.02 (0.77-1.35)

  2004-2005

0.84 (0.61-1.17)

  2006-2007

0.84 (0.57-1.22)

ASA indication

  Cerebrovascular disease

1 (-)

  Myocardial infarction

1.12 (0.82-1.53)

  Ischaemic heart disease

1.06 (0.81-1.39)

  Unstable angina

1.25 (0.60-2.59)

PPI use at start date

  No

1 (-)

  Yes

1.23 (0.93-1.62)

History of PUD at start date

  No

1 (-)

  Yes

2.22 (1.60-3.09)

  1. aHRs estimated by Cox regression analyses and adjusted for all variables in the table.
  2. Abbreviations: ASA-Acetylsalicylic acid; CI-Confidence interval; HRs-Hazard ratios; PPI-Proton pump inhibitor; PUD-Peptic ulcer disease.