Controls N = 2000 n (%) | Uncomplicated PUD cases N = 309 n (%) | Adjusted OR (95% CI) a | |
---|---|---|---|
NSAIDs | 206 (10.3) | 57 (18.4) | 1.50 (1.06-2.13) |
Selective COX-2 inhibitors | 28 (1.4) | 13 (4.2) | 2.33 (1.13-4.79) |
tNSAIDs | 178 (8.9) | 44 (14.2) | 1.36 (0.93-1.99) |
Paracetamol | 492 (24.6) | 114 (36.9) | 1.45 (1.08-1.95) |
Low-dose ASA | 1515 (75.8) | 245 (79.3) | 1.33 (0.87-2.04) |
Clopidogrel | 157 (7.9) | 29 (9.4) | 0.94 (0.60-1.48) |
Oral anticoagulants | 84 (4.2) | 8 (2.6) | 0.68 (0.31-1.48) |
Dipyridamole | 62 (3.1) | 9 (2.9) | 0.78 (0.37-1.62) |
PPIs | 453 (22.7) | 107 (34.6) | 1.68 (1.26-2.25) |
Used on start dateb | 266 (13.3) | 48 (15.5) | 1.25 (0.86-1.80) |
Use initiated after start datec | 187 (9.3) | 59 (19.1) | 2.38 (1.65-3.42) |
H2RAs | 60 (3.0) | 23 (7.4) | 2.26 (1.34-3.82) |
Oral steroids | 58 (2.9) | 21 (6.8) | 1.88 (1.09-3.25) |
SSRIs | 103 (5.2) | 27 (8.7) | 1.45 (0.91-2.32) |
Tricyclic antidepressants | 105 (5.3) | 19 (6.1) | 1.03 (0.61-1.74) |
Statins | 1431 (71.6) | 220 (71.2) | 0.89 (0.65-1.23) |