Skip to main content

Table 3 Association of H. pylori, cagA and EPIYA-C motif number with chronic gastritis, peptic ulcer and gastric cancer

From: The EPIYA-ABCC motif pattern in CagA of Helicobacter pyloriis associated with peptic ulcer and gastric cancer in Mexican population

 

H. pylori

Diagnosis

Negative

Positive

OR

CI 95%

G

182

220

1.0

-

PU

24

53

1.8c

1.0-3.0

GC

6

14

1.9

0.72-5.1

Total

212

287

  
 

CagA

 

Negative

Positive

OR

CI 95%

G

56

164

1.0

-

PU

14

39

0.9

0.5- 1.9

GC

3

11

1.2

0.3 – 4.6

Total

73

214

  
 

EPIYA motif

 

ABC

ABCC

OR

IC95%

G

130

33

1.0

-

PU

14

25

7.0a

3.3 – 15.1

GC

4

6

5.9b

1.5-22.1

Total

148

64

  
 

Number of EPIYA-C

 

1 C*

≥2 Cϕ

OR

IC95%

G

130

34

1.0

-

PU

14

25

6.8a

3.2-15.6

GC

5

6

4.5c

1.3-15.9

Total

149

65

  
  1. G; chronic gastritis, UP peptic ulcer, CG: gastric cancer. ap < 0.001 ; bp <0.01; cp < 0.05. * The EPIYA-ABBC was added; ϕ the EPIYA-ABBCCC was added
  2. Note: Only the most frequent EPIYA motifs were considered.