Skip to main content

Table 2 Kinetic parameters of Na-glutamine co-transport in crypt cell BBMV

From: Mast cell regulation of Na-glutamine co-transporters B0AT1 in villus and SN2 in crypt cells during chronic intestinal inflammation

 

V max (nmol/mg protein•6 sec)

K m (mM)

Control

2.4 ± 0.9

49.6 ± 4.8

Inflamed

2.6 ± 0.4

21.2 ± 4.3*

Inflamed + ketotifen

2.3 ± 0.6

45 ± 0.6*

  1. In crypt cells, the affinity (K m ) of Na-glutamine co-transport which was increased significantly during chronic intestinal inflammation was reversed back to its normal levels by ketotifen treatment (n = 3, *p < 0.01).